Hyaluronan Books Available from MBI

To order any of these books, please visit Matrix Biology Institute's storefront on Amazon.com: http://www.amazon.com/shops/Matrixbiology

I. Five books were created and published during 2011 and 2012 by MBI under the general title: Hyaluronan: From Basic Science to Clinical Applications. General Editor, Endre A. Balazs. Editors: Istvan Hargittai and Magdolna Hargittai.

Volumes 1 and 3: These 2 volumes contain conversations with internationally well-known scientists who have spent most of their research activities on hyaluronan and on the structure and function of the substance between the cells of the vertebrate body – also called the biomatrix.

Volume 2: History of Hyaluronan Science describes the research work of a collection of former scientists who were interested primarily in the structure and biological function of hyaluronan. It also contains a chapter with the title: The Early History of Hyaluronan Research which reviews how hyaluronan was discovered, defined and its biological function analyzed in various tissues during the early days of biomedical uses.

Volume 4: Tivadar Huzella: Scientist and Humanitarian contains lectures in the memory of Huzella's exceptional research work on the importance of the structure and function of the substance that fills the space between the cells of the vertebrate body. The chapters in this book were written by his former students or admirers who knew him personally or read his books. The meeting in the memory of his scientific contributions and his unique humanitarian concepts was held in the auditorium of his former Department of Histology and Embryology of the Medical School of the Peter Pazmany University of Budapest, where he worked between 1932 and 1946.

Volume 5: Structure and Function of Biomatrix – Control of Cell Behavior and Gene Expression. In July 2011, an international meeting was organized in Budapest (Hungary) at the Semmelweis University Medical School in the same auditorium location immediately after the Tivadar Huzella memorial meeting was held. The lecturers at the conference were invited from USA, France, Great Britain, Hungary, Switzerland and Canada because of their biomedical research interests and years of work on the structure and function of the biomatrix – the complicated and highly specific space between the cells of all tissues and organs of the vertebrate body.

Product image Volume 1:
Conversations with Hyaluronan Scientists
by M. Hargittai and I. Hargittai
2011


Featuring conversations with internationally well-known scientists about their work on the subject of their major interest: hyaluronan and glycosaminoglycans: Anthony Day, Paul DeAngelis, Timothy Hardingham, Vincent Hascall, Koji Kimata, Cheryl Knudson, Warren Knudson, Torvard Laurent, Aled Phillips, Glyn Phillips, Glenn Prestwich, John Scott, Robert Stern, Markku Tammi, Raija Tammi, Paul Weigel and Thomas Wight
$20.00 (plus shipping) Buy
Product image Volume 2:
History of Hyaluronan Science
by E.A. Balazs, M. Hargittai and I. Hargittai
2011


A comprehensive, early history of hyaluronan sciences focusing on the work of past leaders: Karl Meyer (by E.A. Balazs), Phoebus Levene, Alexander Ogston, Albert Dorfman, Roger Jeanloz, Robert Cleland and Torvard Laurent (by Istvan and Magdolna Hargittai) and one chapter on the Early History of Hyaluronan Research (by E.A. Balazs)
$20.00 (plus shipping) Buy
Product image Volume 3:
More Conversations with Hyaluronan Scientists
by M. Hargittai and I. Hargittai
2011


Featuring conversations with internationally well-known scientists about their work on the subject of their major interest: hyaluronan and glycosaminoglycans: Mary Cowman, Janet Denlinger, Peter Ghosh, Paraskevi Heldin, Paul Noble, Peter Prehm, Ladislas Robert, John Sheehan, Bryan Toole, Eva Turley, Charles Weiss and Endre A. Balazs
$20.00 (plus shipping) Buy
Product image Volume 4:
Tivadar Huzella: Scientist and Humanitarian
E. A. Balazs and M. Hargittai, Editors
2012


Devoted to one of the initiators of intercellular matrix research: Tivadar Huzella, cytologist and founder of the International Society of Experimental Cytology in 1927.
Authors: Endre A. Balazs (USA), Ágoston Szél (Hungary), Istvan Hargittai (Hungary), Anna Erdei (Hungary), Georg Klein (Hungary), Janos A. Szirmai (Netherlands), Ladislas Robert (France), László Módis (Hungary) and Szabolcs Felszeghy (Hungary).
$20.00 (plus shipping) Buy
Volume 5: Structure and Function of Biomatrix: Control of Cell Behavior and Gene Expression
E. A. Balazs, Editor
2012


A unique collection of review articles written by 11 scientists from the United States, France, Hungary, Great Britain, Switzerland and Canada.
Authors: Matthias Chiquet, Mary Cowman, Catherine Picart, Sylvie Ricard-Blum, Ladislas Robert, Bryan Toole, Vincent Hascall, James H-C Wang, Paul Weigel, Thomas Wight, Jessica C.F. Kwok
$20.00 (plus shipping)
5 Volume Set Purchase all 5 volumes together for only $60.00 (plus shipping)

II. Historically-interesting volumes available from Matrix Biology Institute

Hyaluronic Acid and Matrix Implantation Product image Arlington, MA (USA)
by Endre A. Balazs, 168 pages, 1971
$20.00 (plus shipping) Buy

The use of hyaluronan as a therapeutic agent was first suggested in 1941 by Endre A. Balazs. The idea was based on experiments on wound healing and on the regeneration of synovial fluid after traumatic injuries. In 1958, Balazs suggested that extremely viscous hyaluronan solutions could be used to replace the vitreus after retinal surgery. This book reviews the suggested therapeutic uses of highly purified, viscoelastic hyaluronan solutions, both in eye surgery and in the treatment of intra-articular damage caused by arthritis.
The first 147 pages of this book describe in detail the experimental work carried out in Balazs’ laboratory on the effect of the highly purified, viscoelastic hyaluronan in intravitreal, intraperitoneal and intra-articular applications in animals. Human clinical trials on intravitreal, intradermal, intra-articular application, as well as the veterinary trials after joint injury, are also reported. The effect of hyaluronan on cell activities in healing wounds, on extravascular immunoreactions and on cell assemblies is also reported.
The appendix of the book contains 13 publications (in full length) produced between 1968 and 1971 on the therapeutic use of hyaluronan produced by Balazs’ company, Biotrics, Inc. (Massachusetts, USA) and used by clinical clinicians and scientists in the USA , France, Germany, Switzerland and Sweden.
This book was written to be used as a tool to identify a pharmaceutical company to manufacture and sell purified hyaluronan for use in the eye and the joint.

Metabolism of Sodium Hyaluronate in Articular and Ocular Tissues Product image by Janet L. Denlinger, 327 pages, 1982
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The joint and the eye share a very significant structural and biochemical feature: both contain a central liquid compartment surrounded by, and in direct contact with, solid matrices of connective tissue. No cellular or membranous barrier exists. In both of these structures, the main component of the liquid compartment is hyaluronan.
Because of developments making a wide range of hyaluronans available for therapeutic use, it was important to know how the hyaluronan content of the joint and eye changed during various artificially-created inflammatory conditions, and how an excess amount of hyaluronan applied to these tissue compartments was metabolized. Another area of investigation was how hyaluronan influences cellular adhesion and other functions of cells, especially those of the lymphomyeloid system.
This book summarizes the research by the author in the early 1980s, and reviews the associated literature on these subjects.

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III. Also Available

Product image The Chemistry, Biology and Medical Applications of Hyaluronan and its Derivatives
Torvard C. Laurent, Editor
341 pages, Hardcover
$25.00 (plus shipping) Buy


The aim of this book is to collect information on hyaluronan within one volume. This polysaccharide has received rapid attention for two reasons: it has important regulative functions within cell biology, and it has become a commercially important product because of its use in ophthalmic surgery and treatment of joint disease. A number of other practical applications are also discussed. The book covers various aspects of hyaluronan from the structure and chemistry of the polymer to its metabolism, cell biological interactions, behavior in pathological processes, and potentially new medical applications. This book should interest those working in the fields of biochemistry, cell biology, physiology and ophthalmology, as well as research scientists in the pharmaceutical industry.
Product image Hyaluronan: Structure, Metabolism, Biological Activities, Therapeutic Applications
E.A. Balazs and V.C. Hascall, Editors
2 Volume Set - 912 pages, Hardcover.
$50.00 (plus shipping) Buy


This two-volume book set contains 131 papers representing all aspects of hyaluronan science. This book is based on the lectures and posters presented at the VI International Meeting on Hyaluronan (Cleveland, Ohio). It is a "must read" for hyaluronan researchers and will be a most appreciated gift for clinical and laboratory scientists who want to learn the latest research results related to hyaluronan and its therapeutic applications. This book is dedicated to Torvard C. Laurent for his extraordinary contributions to hyaluronan science during the past half century.
Product image The Magic Molecule That Has Improved the Lives of Millions
by Borje Svensson
2015


$28.00 (plus shipping) Buy


To order any of these books, please visit
Matrix Biology Institute’s storefront on Amazon.com: http://www.amazon.com/shops/Matrixbiology